Aging and Human Visual Function

Abstract

McArdle9s disease is a metabolic myopathy of glycogen utilization caused by an absence or deficiency of myophosphorylase.The muscle biopsy features include increased deposition of subsarcolemmal glycogen and absent phosphorylase histochemical staining of myofibers. We report the clinical and unique pathologic findings in three cases of McArdle9s disease with prominent type 1 fiber atrophy. <b>NEUROLOGY 1996;47: </b> 581-583