Amino acids exhibit anti-inflammatory effects in human monocytic leukemia cell line, THP-1 cells

Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease

Daniel H. Present, Paul Rutgeerts, Stephan Targan et al. · New England Journal of Medicine · 1999 · 2.7K citations · Full text

Medicine, Clinical Sciences, Pharmacotherapy +14

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

Towia A. Libermann, David Baltimore · Molecular and Cellular Biology · 1990 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +16

Efficacy and safety of retreatment with anti–tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease

Paul Rutgeerts, Geert D’Haens, Stephan R. Targan et al. · Gastroenterology · 1999 · 1.1K citations · Full text

Life Sciences, Immunology, Pharmacotherapy +10

Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.

Taiji Matsusaka, Kazuo Fujikawa, Yukihiro Nishio et al. · Proceedings of the National Academy of Sciences · 1993 · 963 citations

Life Sciences, Immunology, Molecular Biology +16

Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B.

Martine A. Collart, Patrick A. Baeuerle, P Vassalli · Molecular and Cellular Biology · 1990 · 888 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16