Journal of Natural Products · 2000 · 97 citations · 11 references
Natural SciencesMarine BiologyMarine SciencesAntimicrobial PharmacologyMarine BiodiversityMarine EcologyAntibacterial AgentsAntibacterial PharmacologyCrustacean ZoologyMarine Bioactive CompoundsMarine Drug DiscoveryMarine Natural ProductsAntimicrobial Marine CompoundsBioactive Compounds From Marine SpongesBioactive Marine MetabolitesMarine PharmacognosyMarine Sponge MetabolitesMarine-derived Antimicrobial CompoundsSponges As Drug SourcesSponges-derived Metabolites
Two sponges belonging to the family Latrunculiidae (Negombata and Latrunculia sp.) collected during scientific trawling operations in Prydz Bay, Antarctica, and by scuba off Port Campbell, Victoria, have yielded a new antibacterial pyrroloiminoquinone, discorhabdin R (2). The structure was assigned as 2 on the basis of detailed spectroscopic analysis and comparison with the known co-metabolite discorhabdin B (3).
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