Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

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Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

Luca Santarelli, Michael Saxe, Cornelius T. Gross et al. · Science · 2003 · 4.3K citations · Full text

Medicine, Neurobiology, Neuroscience +16

The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function

Michael Egan, Masami Kojima, Joseph H. Callicott et al. · Cell · 2003 · 3.9K citations · Full text

Life Sciences, Genetics, Neuroscience +8

The use of a plus-maze to measure anxiety in the mouse

Richard G. Lister · Psychopharmacology · 1987 · 2.6K citations

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Causal Relationship Between Stressful Life Events and the Onset of Major Depression

Kenneth S. Kendler, Laura M. Karkowski, Carol A. Prescott · American Journal of Psychiatry · 1999 · 2.5K citations

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