Cancer · 1967 · 98 citations · 2 references
MedicineOncologyPathologyPulmonologyThoracic OncologyTumor PathologyAirway DiseasesLung CancerRespiratory PathologyThoracic Tumor PathologyTumor HistopathologyLung Cancer PathologyTracheobronchial DiseaseTracheobronchial Tumor
From 50 to 208 sections of the tracheobronchial tree of each of 255 patients who died of bronchial carcinoma were microscopically examined. Lesions histologically classified as primary invasive carcinoma (other than the main tumor mass) were found in 77 sections; lesions similar but of somewhat less certain character were found in 26 sections. Such lesions were found in 37 of the 255 subjects (22 subjects had just one; 15 had two or more). The locations of the lesions were studied in relation to the location of the main tumor mass. Using strict criteria, we concluded that at least nine (3.5%) of the patients had multiple primary bronchial carcinomas (two or more including the original tumor). Using less strict criteria (i.e., the inclusion of cases where varying degrees of uncertainty existed) the number might be as high as 37 (14.5%).
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