Concepedia

CpG oligodeoxynucleotides as immunotherapy in cancer

Bernd Jahrsdörfer, George J. Weiner

Update on Cancer Therapeutics · 2008 · 133 citations · 36 references

DOIFull text

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Concepts

References

36

A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai et al. · Nature · 2000 · 6.4K citations

, , +13

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

, , +10

Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA

Zuhair K. Ballas, Wendy Rasmussen, A M Krieg · The Journal of Immunology · 1996 · 755 citations · Full text

, , +15

Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909

Daniel E. Speiser, Danielle Líénard, Nathalie Rufer et al. · Journal of Clinical Investigation · 2005 · 622 citations · Full text

, , +17

Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

George J. Weiner, Hsin-Ming Liu, James E. Wooldridge et al. · Proceedings of the National Academy of Sciences · 1997 · 522 citations

, , +17