Macromolecular Chemistry and Physics · 1998 · 41 citations · 0 references
Natural SciencesBiomedical EngineeringMaterials ScienceBiocompatibilityBiomaterialsPolymer ChemistryPolymer ProcessingPolymer SurfacesPolymer Thin FilmsPolymeric BiomaterialsPolymerization ChemistrySurface ModificationBiocompatibility ImprovementGraft CopolymerizationPolymer BiocompatibilityPolymer GraftingPolymer Grafting Onto SurfacesPolymer ModificationPolymer Surface ModificationPolymerization Of Vinyl Monomers
Surface modified poly(ethylene terephthalate) (PET) films with 2-(methacryloyloxy)ethylphosphorylcholine (MPC) and 2-(glucosyloxy)ethyl methacrylate (GEMA) moieties, PMPC-g-PET and PGEMA-g-PET, were prepared by graft copolymerization using an Ar plasma-post polymerization technique. The degrees of polymerization of the grafts PMPC and PGEMA were P̄n ≈ 30 and P̄n ≈ 40, respectively. The contact angle of the modified PET film decreased from θ = 68° (the original PET film) to θ = 26° for PMPC-g-PET and to θ = 43° for PGEMA-g-PET. The modified PET films adsorb less serum proteins than the original PET film. Egg yolk lecithin did not adsorb on PGEMA-g-PET but adsorbed on PMPC-g-PET. PMPC-g-PET showed activity for the inhibition of fibrin formation and no adhesion of mouse fibroblasts (L-929).