Science · 1978 · 334 citations · 126 references
Life SciencesNeurosciencePsychologyBehavioral NeuroscienceNeurochemistryNeuropharmacologyBehavior TherapyBehavioral PhysiologyBrain-behavior RelationshipsEmotion DysregulationEmotion ProcessingNeuromodulationAffective Behavior ChangesBehavioral TypesNeurochemical ModulationNeurochemical SignalingNeurophysiology Of Behavior
There is compelling evidence that behavioral events after neurochemical function and that altered neurochemical function can change behavior. Such processes have been related both to neurotransmitters and to neuromodulators, together termed neuroregulators. Available research tools and theoretical constructs have begun to permit studies of certain types of behavior, primarily those related to emotional states and drives. This work is changing long-held concepts about severe mental disorders and the treatment of them.
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Identification of two related pentapeptides from the brain with potent opiate agonist activity
Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations
Opiate Receptor: Demonstration in Nervous Tissue
Candace B. Pert, Solomon H. Snyder · Science · 1973 · 2.4K citations
Medicine, Neuroscience, Pharmacology +10
Antipsychotic drug doses and neuroleptic/dopamine receptors
Philip Seeman, T. Lee, M. Chau-Wong et al. · Nature · 1976 · 1.6K citations
Medicine, Pharmacology, Psychiatry +13
Chemical Nature of Synaptic Transmission in Vertebrates
K. Krnjević · Physiological Reviews · 1974 · 1.6K citations