IgG heavy-chain deposition disease affecting kidney, skin, and skeletal muscle

Abstract

Key words: deposition disease; heavy chain; immuno-ance 48 ml/min), urea 15.3 mmol/l. Serum cholesterol globulin G; kidney; skeletal muscle; nodular glomwas slightly elevated (6.3 mmol/l ). The patient had erulosclerosis; skin low complement components, C3 and C4 (0.22 and 0.04 g/l respectively), positive antinuclear antibodies in low titre, positive antibodies to glomerular basement membrane (BM ) antigens (21 EU ), without detectable