A randomized crossover study to evaluate Ro 115–1240, a selective α _1A/1L ‐adrenoceptor partial agonist in women with stress urinary incontinence

Abstract

This study suggests that selective alpha1A/1l-adrenoceptor partial agonists have the potential to improve the symptoms of SUI with little or no cardiovascular effect. These results are encouraging and a randomized controlled trial of Ro 115-1240 in a larger population with SUI is warranted to substantiate these findings.