Concepedia

Pancratistatin: A natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis

Andrew J. McLachlan, Natasha Kekre, James McNulty, Siyaram Pandey

APOPTOSIS · 2005 · 154 citations · 18 references

DOI

Concepts

References

18

The Pathophysiology of Mitochondrial Cell Death

Douglas R. Green, Guido Kroemer · Science · 2004 · 3.4K citations

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Mitochondrial Complex I Inhibitor Rotenone Induces Apoptosis through Enhancing Mitochondrial Reactive Oxygen Species Production

Nianyu Li, Kathy Ragheb, Gretchen Lawler et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

, , +17

Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

Aurélien Olichon, Laurent Baricault, Nicole Gas et al. · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

, , +17

Somatic mutations of the mitochondrial genome in human colorectal tumours

Kornélia Polyák, Yunbo Li, Hong Zhu et al. · Nature Genetics · 1998 · 838 citations

, , +16

Paraquat induces oxidative stress and neuronal cell death; neuroprotection by water-soluble Coenzyme Q10

Susan A. McCarthy, Mallika Somayajulu, M. Sikorska et al. · Toxicology and Applied Pharmacology · 2004 · 248 citations

, , +16