Concepedia

Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes

Ulrich Lächelt, Petra Kós, Frauke Martina Mickler, Annika Herrmann, Eveline E. Salcher, Wolfgang Rödl, Naresh Badgujar, Christoph Bräuchle, Ernst Wagner

Nanomedicine Nanotechnology Biology and Medicine · 2013 · 129 citations · 30 references

DOI

Concepts

References

30

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

, , +17

Exploring polyethylenimine‐mediated DNA transfection and the proton sponge hypothesis

Akin Akinc, Mini Thomas, Alexander M. Klibanov et al. · The Journal of Gene Medicine · 2004 · 1.3K citations

, , +14

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

S. Moein Moghimi, Peter Symonds, J. Clifford Murray et al. · Molecular Therapy · 2005 · 1.1K citations · Full text

, , +17

Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes

N.D. Sonawane, Francis C. Szoka, A.S. Verkman · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

, , +14

The Proton Sponge: a Trick to Enter Cells the Viruses Did Not Exploit

Jean‐Paul Behr · CHIMIA International Journal for Chemistry · 1997 · 921 citations · Full text

, , +17