Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 92.8K citations

Bioinformatics, Engineering, Information Retrieval +10

The Pfam Protein Families Database

Alex Bateman · Nucleic Acids Research · 2002 · 14.2K citations · Full text

Bioinformatics, Biochemistry, Structural Bioinformatics +12

The DNA sequence of human chromosome 21

Masahira Hattori, Asao Fujiyama, Todd D. Taylor et al. · Nature · 2000 · 1.5K citations · Full text

Chromatin, Developmental Biology, Cytogenetics +14

A mouse model for Down syndrome exhibits learning and behaviour deficits

Roger H. Reeves, Nicholas G. Irving, Timothy H. Moran et al. · Nature Genetics · 1995 · 906 citations

Down Syndrome, Behavioral Sciences, Neuropsychology +14

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

Kay Hofmann, Philipp Bücher · Trends in Biochemical Sciences · 1996 · 401 citations

Protein Function, Biochemistry, Natural Sciences +9