Lactobacillus crispatus Capsules: Single-Use Safety Study in the Macaca nemestrina Model

Abstract

A single intravaginal application of capsules containing 108 L crispatus CTV-05 resulted in vaginal colonization in three of 10 animals 2 days after use. The absence of colposcopic changes in the vagina/cervical tissues indicates that L crispatus capsules are well tolerated.