Circulating Endothelial Microparticle Levels Predict Hemodynamic Severity of Pulmonary Hypertension

Abstract

In subjects with precapillary PH, levels of circulating endothelial and leukocyte MPs were increased compared with control subjects. In addition, levels of PECAM(+) and VE-cadherin(+), but not E-selectin(+), endothelial MPs predicted hemodynamic severity of the disease.