Interaction of MK-801 with the nicotinic acetylcholine receptor-associated ion channel from electroplax

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Erik H.F. Wong, J A Kemp, Tony Priestley et al. · Proceedings of the National Academy of Sciences · 1986 · 1.8K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

Nabil A. Anis, Stephen C. Berry, N.R. Burton et al. · British Journal of Pharmacology · 1983 · 1.4K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.

James E. Huettner, Bruce P. Bean · Proceedings of the National Academy of Sciences · 1988 · 755 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Phencyclidine interactions with the ionic channel of the acetylcholine receptor and electrogenic membrane

Edson X. Albuquerque, Ming-Cheng Tsai, Robert S. Aronstam et al. · Proceedings of the National Academy of Sciences · 1980 · 89 citations · Full text

Medicine, Pharmacology, Physiology +17

[3H]Phencyclidine: a probe for the ionic channel of the nicotinic receptor.

Mohyee E. Eldefrawi, Amira T. Eldefrawi, Robert S. Aronstam et al. · Proceedings of the National Academy of Sciences · 1980 · 79 citations · Full text

Medicine, Neuroscience, Pharmacology +17