Calcium ion-stimulated phosphorylation of myelin proteins

P V Sulakhe, Elena H. Petrali, Brenda J. Thiessen, Evelyn R. Davis

Biochemical Journal · 1980 · 33 citations · 20 references

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Abstract

Myelin isolated from the central and peripheral nervous system contains a Mg2+-dependent protein kinase that catalyses phosphorylation of myelin-specific proteins. This phosphorylation is markedly stimulated by Ca2+ but not by cyclic AMP. Evidence was obtained that suggested an involvement of calmodulin-like protein in the stimulatory effects of Ca2+ on myelin phosphorylation.

References

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