Chemical Communications · 2015 · 83 citations · 32 references
Natural SciencesChemical EngineeringChemistryAnalytical ChemistryMass Spectrometric AnalysisPolymer ChemistryPolymer AnalysisPolymer StructurePolymer SynthesisPolymerization ChemistryPolymerization KineticsPolymerization ProcessesElectrospray IonizationElectrospray Ionization CouplingMicroreactor TechnologyPolymer Mass SpectrometryPolymerization Process ControlPolymerization ReactionsReal-time MonitoringReal-time Processing
A technique for the continuous on-line monitoring of polymerization processes by electrospray ionization mass spectrometry (ESI-MS) is presented via coupling with a commercial microreactor system. The potential is demonstrated by monitoring polymerizations in real time under synthesis conditions. Furthermore, a single acrylate monomer insertion into a oligo-RAFT agent, as used in the synthesis of monodisperse sequence controlled materials, was optimized by on-line screening of reaction conditions.
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