Gadolinium released from MR contrast agents is deposited in brain tumors: <i>in situ</i> demonstration using scanning electron microscopy with energy dispersive X-ray spectroscopy

Abstract

Gd-containing deposits are present in brain tumors following contrast-enhanced MR scans in patients without severe renal disease. Further studies are needed to assess the clinical importance of the deposits we observed and to determine whether they are also found in other conditions that alter the integrity of the BBB.