Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prostaglandin E₂ on this release from peripheral blood leucocytes in aspirin‐induced asthmatic patients

Abstract

The increase in Cys-LT levels following ASA stimulation seems to be unique to AIA, which was not present in patients with ATA and in healthy controls. The inhibitory effect of PGE(2) on stimulated Cys-LT levels is another important finding to elucidate the role of PGE(2) in the pathogenesis of AIA.