MedicinePharmacotherapySurgeryAnesthesiaChemotherapyLocal AnesthesiaAnalgesiaAntiemetic TherapySymptom ManagementAntiemetic Efficacy EvaluationComparative Effectiveness Of AntiemeticsNonpharmacologic Symptom Relief
In a strictly controlled clinical situation, (postoperative sickness) where variables were reduced to a minimum, it was possible to demonstrate an effective prophylactic antiemetic action of P6 (Neiguan) acupuncture. Manual and electrical invasive (needling) stimulation of this point were equally effective. Non-invasive stimulation (transcutaneous electrical or pressure) was effective in the early postoperative period, but the effect did not last as long as for invasive acupuncture--although it was as good as standard antiemetics. Stimulation of a "dummy" acupuncture point was ineffective as was administration of the acupuncture after the emetic stimulus (opioid). This effect can be blocked by local anaesthesia at the P6 point. Acupressure (P6) is moderately effective in reducing morning sickness, but here there is more of a psychological element as pressure on a "dummy" point gives some alleviation of symptoms. Given in conjunction with standard antiemetics, P6 acupuncture is a useful adjuvant in reducing sickness after cancer chemotherapy. This effect can be prolonged for 24 hours by acupressure.
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Richard J. Gralla, Loretta M. Itri, Sharon E. Pisko et al. · New England Journal of Medicine · 1981 · 710 citations
Traditional Chinese acupuncture: a potentially useful antiemetic?
J. W. Dundee, W. N. Chestnutt, R. G. Ghaly et al. · BMJ · 1986 · 214 citations · Full text
Medicine, Pharmacotherapy, Surgery +16
Acupuncture Prophylaxis of Cancer Chemotherapy-Induced Sickness
JOHN W. DUNDEE, R. G. Ghaly, Katherine Fitzpatrick et al. · Journal of the Royal Society of Medicine · 1989 · 177 citations · Full text
Medicine, Oncology, Pharmacotherapy +10
P6 Acupressure Reduces Morning Sickness
JOHN W. DUNDEE, F B R Sourial, R. G. Ghaly et al. · Journal of the Royal Society of Medicine · 1988 · 115 citations · Full text
Management of Nausea and Vomiting in the Cancer Patient
Stephen Frytak · JAMA · 1981 · 91 citations