The relationship between the binding to and permeabilization of phospholipid bilayer membranes by GS14dK4, a designed analog of the antimicrobial peptide gramicidin S

Gramicidin S and its use in the Treatment of Infected Wounds

G. F. Gause, M G Brazhnikova · Nature · 1944 · 299 citations

Veterinary Medicine, Medicinal Chemistry, Microbiology +14

Dissociation of Antimicrobial and Hemolytic Activities in Cyclic Peptide Diastereomers by Systematic Alterations in Amphipathicity

Leslie H. Kondejewski, Masood Jelokhani‐Niaraki, Susan Walker Farmer et al. · Journal of Biological Chemistry · 1999 · 244 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Modulation of Structure and Antibacterial and Hemolytic Activity by Ring Size in Cyclic Gramicidin S Analogs

Leslie H. Kondejewski, Susan Walker Farmer, David S. Wishart et al. · Journal of Biological Chemistry · 1996 · 182 citations · Full text

Life Sciences, Biochemistry, Drug Design +16

Membrane Binding and Pore Formation of the Antibacterial Peptide PGLa:  Thermodynamic and Mechanistic Aspects

Torsten Wieprecht, Ognjan Apostolov, Michael Beyermann et al. · Biochemistry · 1999 · 181 citations

Natural Sciences, Biochemistry, Biophysics +17

Nonlamellar Phases Induced by the Interaction of Gramicidin S with Lipid Bilayers. A Possible Relationship to Membrane-Disrupting Activity

Elmar J. Prenner, Ruthven N.A.H. Lewis, Keir C. Neuman et al. · Biochemistry · 1997 · 135 citations

Natural Sciences, Biochemistry, Biophysics +17