Trimetazidine protects cardiomyocytes against hypoxia-induced injury through ameliorates calcium homeostasis

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

The Antianginal Drug Trimetazidine Shifts Cardiac Energy Metabolism From Fatty Acid Oxidation to Glucose Oxidation by Inhibiting Mitochondrial Long-Chain 3-Ketoacyl Coenzyme A Thiolase

Paul F. Kantor, Arnaud Lucien, Raymond Kozak et al. · Circulation Research · 2000 · 807 citations

Medicine, Cardiology, Pharmacology +17

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

Iftach Shaked, Ari Meerson, Yochai Wolf et al. · Immunity · 2009 · 423 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +12

Functional Coupling Between Glycolysis and Sarcoplasmic Reticulum Ca ²⁺ Transport

Kai Xu, Jay L. Zweíer, Lewis C. Becker · Circulation Research · 1995 · 311 citations

Life Sciences, Biochemistry, Cell Biology +17

Elevated Sarcoplasmic Reticulum Ca ²⁺ Leak in Intact Ventricular Myocytes From Rabbits in Heart Failure

Thomas R. Shannon, Steven M. Pogwizd, Donald M. Bers · Circulation Research · 2003 · 308 citations

Medicine, Cardiology, Physiology +17