Chronic Ethanol Consumption by C57BL/6 Mice Promotes Tolerance to Its Interoceptive Cues and Increases Extracellular Dopamine, an Effect Blocked by Naltrexone

Abstract

B6 mice voluntarily consume sufficient ethanol (1) to produce intoxicating BEL; (2) to increase DA levels in nucleus accumbens, an effect blocked by naltrexone; and (3) to attenuate its discriminative cues.