Susceptibility of Related Vibrios and <i>Vibrio Fetus</i> to Twelve Antibiotics

Abstract

One hundred fourteen strains of related vibrio and seven strains of Vibrio fetus, all isolated from humans, were tested for susceptibility in vitro to 12 antibiotics. Mueller-Hinton agar containing 14 dilutions of the antibiotics was inoculated with undiluted overnight cultures. Gentamicin and erythromycin were the most active drugs against related vibrios and Vibrio fetus; lower activity was noted with chloramphenicol, streptomycin, and tetracycline; neomycin and kanamycin were even less active. The susceptibility to ampicillin was variable. More than 90% of the strains were resistant to cephalothin.