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THE TEMPORAL RELATIONSHIP BETWEEN GONADOTROPIN RELEASING HORMONE (GnRH) AND LUTEINIZING HORMONE (LH) SECRETION IN OVARIECTOMIZED EWES<sup>1</sup>
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1982
Year
GynecologyReproductive BiologyReproductive EndocrinologyReproductive PhysiologyPituitary GlandNeuroendocrine MechanismHypothalamic PeptidePublic HealthLh SecretionAnimal PhysiologyPituitary FunctionLuteinizing HormoneNervous SystemEndocrinologyAnimal ReproductionTheriogenologyPortal PlasmaNeurophysiologyAnimal ScienceNeuroanatomyPhysiologyReceptor BiologyCentral Nervous SystemMedicineReproductive HormoneGonadotropin Biology
Hypothalamo-hypophyseal portal blood has been collected from conscious OVX ewes by a procedure that permits maintenance of pituitary function. GnRH was measured in portal plasma and LH was measured in peripheral (jugular) plasma. The data demonstrate exact synchrony of GnRH and LH secretion. We conclude that each pulsatile LH secretory episode results from a pulsatile discharge of GnRH from the hypothalamus via the portal network