Publication | Closed Access
Morphine recognition by a porphyrin–cyclocholate molecular bowl
50
Citations
9
References
1993
Year
Molecular PharmacologyMedicinal ChemistryPharmaceutical ScienceBiochemistryMedicineNatural SciencesPhilosophy Of ChemistryMorphine RecognitionMolecular BowlNitrogen–metal LigationHydrogen BondingChemical ProbeChemical BiologyPharmacologyBiophysicsDrug DiscoveryBio-orthogonal Chemistry
A molecular bowl has been prepared by constructing a metalloporphyrin on one face of a tetrameric cyclocholate; the bowl selectively binds morphine by a combination of nitrogen–metal ligation and hydrogen bonding.
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