Manganese‐Catalyzed Insertion of Aldehydes into a CH Bond

Abstract

Mn gets in the game: In the presence of a manganese catalyst and a stoichiometric amount of hydrosilane, aldehydes insert into CH bonds of aromatic rings of compounds with directing groups (see scheme). This first example of a manganese-catalyzed chemical transformation through CH bond activation gives silyl ethers in good to excellent yields and can also be applied to asymmetric transformation.