Anti-insulin receptor autoantibodies in a patient with type B insulin resistance and fasting hypoglycemia

Insulin‐like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

A. Ullrich, Andrew Gray, Albert W. Tam et al. · The EMBO Journal · 1986 · 1.9K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

The Syndromes of Insulin Resistance and Acanthosis Nigricans

C. Ronald Kahn, Jeffrey S. Flier, Robert S. Bar et al. · New England Journal of Medicine · 1976 · 1.1K citations

Medicine, Endocrinology, Immunology +13

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

Chao‐Kai Chou, Thomas J. Dull, David Russell et al. · Journal of Biological Chemistry · 1987 · 649 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15

Estimates of<i>In Vivo</i>Insulin Action in Man: Comparison of Insulin Tolerance Tests with Euglycemic and Hyperglycemic Glucose Clamp Studies*

Enzo Bonora, Paolo Moghetti, Carlo Zancanaro et al. · The Journal of Clinical Endocrinology & Metabolism · 1989 · 525 citations

Medicine, Endocrinology, Diabetology +12

Antibodies That Impair Insulin Receptor Binding in an Unusual Diabetic Syndrome with Severe Insulin Resistance

Jeffrey S. Flier, C. Ronald Kahn, Jesse Roth et al. · Science · 1975 · 440 citations

Medicine, Endocrinology, Immunology +15