Pranlukast Attenuates Hydrogen Peroxide–induced Necrosis in Endothelial Cells by Inhibiting Oxygen Reactive Species–mediated Collapse of Mitochondrial Membrane Potential

Abstract

Pranlukast protects endothelial cells from H2O2-induced necrosis by inhibiting ROS-mediated collapse of mitochondrial membrane potential, and this is leukotriene-independent.