Thresholds of clinical reactivity to milk, egg, peanut and sesame in immunoglobulin E‐dependent allergies: evaluation by double‐blind or single‐blind placebo‐controlled oral challenges

Abstract

The risk of asthma and anaphylactic shock to sesame and peanut is confirmed. Minimal reactive quantities show that, in order to guarantee a 95% safety for patients who are allergic to egg, peanut and milk, and on the basis of consumption of 100 g of food, the detection tests should ensure a sensitivity of 10 p.p.m. for egg, 24 p.p.m. for peanut and 30 p.p.m. for milk proteins. Oil allergies being considered, the limit of sensitivity should fall to 5 p.p.m.