Phosphorescent proteins for bio-imaging and site selective bio-conjugation of peptides and proteins with luminescent cyclometalated iridium(iii) complexes

Hoi‐Yan Shiu, Hiu-Chi Chong, Yun‐Chung Leung, Taotao Zou, Chi‐Ming Che

Chemical Communications · 2014 · 41 citations · 21 references

Concepts

Abstract

A new bio-conjugation reaction for site selective modification of proteins and peptides with phosphorescent iridium(III) complexes has been developed; the Ir(III)-modified proteins and peptides display long emission lifetimes and large Stoke shifts that can be used for bio-imaging studies.

References

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