Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidum.

Abstract

The 70% MeOH extract of Ganoderma lucidum had an inhibitory effect on angiotensin converting enzyme activity, and from this extract, five new triterpenes, named ganoderal A, ganoderols A and B, and ganoderic acids K and S, were isolated. Their structures were determined on the basis of spectral evidence.