American Journal of Hospice and Palliative Medicine® · 2013 · 28 citations · 10 references
MedicineNeurologyPharmacotherapyPain ManagementPain MedicinePain ScienceAnalgesiaNeuromodulation For PainNeurostimulationPeripheral Nerve StimulationPharmacologic Pain TherapyNeuromodulatory StimulationNeuropathic Pain ReductionNeuropathic Pain ReliefPain Management In NeuropathyPain Score ReductionPharmacological Pain ReliefRefractory Neuropathic Pain
OBJECTIVES: Postherpetic neuropathy (PHN) is common, severe, and often refractory to treatment. We treated 10 patients with refractory PHN using Scrambler therapy, a neurocutaneous stimulation device that delivers "nonpain" information with surface electrodes. METHODS: Scrambler therapy was given as 30-minute sessions daily for 10 days. Pain was recorded before and after treatment. Two centers. RESULT: The average pain score rapidly diminished from 7.64 ± 1.46 at baseline to 0.42 ± 0.89 at 1 month, a 95% reduction, with continued relief at 2 and 3 months. Patients achieved maximum pain relief with less than 5 treatments. DISCUSSION: Scrambler therapy appears to have a promising effect on PHN, with prompt and continued relief and no side effects. Further research is warranted.
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EFNS guidelines on pharmacological treatment of neuropathic pain
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