Concepedia

The synthesis of XTT: A new tetrazolium reagent that is bioreducible to a water‐soluble formazan

Kenneth D. Paull, Robert H. Shoemaker, Michael R. Boyd, Jack L. Parsons, Prabhakar Risbood, William A. Barbera, Mahenda N. Sharma, David C. Baker, E. Hand, Dominic A. Scudiero,

Journal of Heterocyclic Chemistry · 1988 · 151 citations · 7 references

DOI

Concepts

Abstract

Abstract A new tetrazolium salt, XTT, has been synthesized. XTT is reduced by a considerable variety of cell lines to a water‐soluble formazan. XTT appears to merit further investigation as a reagent for broader application to cell culture assay systems.

References

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