Concepedia

Assessment of Tumoral PD-L1 Expression and Intratumoral CD8+ T Cells in Urothelial Carcinoma

Sheila F. Faraj, Enrico Munari, Güneş Güner, Janis M. Taube, Robert A. Anders, Jessica Hicks, Alan K. Meeker, Mark Schoenberg, Trinity J. Bivalacqua, Charles G. Drake,

Urology · 2015 · 183 citations · 28 references

Concepts

MedicineImmunologyOncologyCancer ImmunologyTumor ImmunologyTumor MicroenvironmentAntitumor T Cell ResponsesCancer ImmunotherapyCytotoxic T Lymphocyte ResponsesImmune Cell InfiltrationTumor-infiltrating LymphocytesUrothelial CarcinomaCd8 Positive T CellsCd8+ Tumor-infiltrating LymphocytesPd-1 SignalingPd-l1 BlockadeProgrammed Cell Death Protein 1 (Pd-1) PathwayProgrammed Death-ligand 1 BiomarkerT Cell Infiltration Enhancement

References

28

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

Suzanne L. Topalian, F. Stephen Hodi, Julie R. Brahmer et al. · New England Journal of Medicine · 2012 · 12.7K citations · Full text

Life Sciences, Immunology, Oncology +17

Cancer statistics, 2013

Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2013 · 11.9K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM

Stephen B. Edge, Carolyn C. Compton · Annals of Surgical Oncology · 2010 · 9.2K citations · Full text

Medicine, Oncology, Surgery +14

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

Jérôme Galon, Anne Costes, Fátima Sánchez‐Cabo et al. · Science · 2006 · 6.5K citations

Medicine, Immunology, Oncology +17

AJCC Cancer Staging Manual

James R. Egner · JAMA · 2010 · 6.1K citations

Medicine, Oncology, Surgery +9