Asymmetric Synthesis of Alanine by Catalytic Hydrogenation of Chiral <i>N</i>α-Acetyldehydroalaninamides

Abstract

Abstract Asymmetric hydrogenation of chiral Nα-acetyldehydroalaninamides was studied. The asymmetric yield of the resulting alanine was in the range 0–24%. The effects of reaction temperature, solvent polarity and asymmetric moieties on the asymmetric yields were examined.