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BLOOD CHEMISTRY OF ADRENAL INSUFFICIENCY IN CATS†

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1934

Year

Abstract

The purpose of the experiments described in this paper was to find some criterion for the level of activity of the adrenal cortex similar to the tests now in use for other endocrine glands, such as blood sugar level for the islands of Langerhans, basal metabolism for the thyroid, or calcium and phosphorous values for the parathyroid. Changes in the blood chemistry of animals suffering from adrenal insufficiency have been reported by many investigators using cats (1) (2) (3) (4) (5), dogs (6) (7) (8) (9) (10) (11), and rats (12) (13). The variety of constituents studied and the variable results obtained led us to check a number of the more striking results. A composite picture proved to have a good critical value in the determination of adrenal insufficiency, but an increase in serum potassium and a loss of Na and Cl seem to us to have the greatest specific value.