Pain · 1986 · 142 citations · 8 references
Pain TherapyPain MedicinePsychotropic MedicationNeuropathic PainPharmacotherapyConsecutive PatientsPain ManagementNarcotic/antidepressant MedicationHealth SciencesLong-term UsePsychiatryPostoperative Pain ManagementPhantom Limb PainSuccessful ManagementNeuropharmacologyRehabilitationPhysical TherapyPain TreatmentPain ResearchDrug TherapyAnesthesiaMedicineAnesthesiology
The successful management of 5 consecutive patients with intractable phantom limb pain is described. The main therapy is a combination of a narcotic and antidepressant. Medication remained effective during the average observation time of 22 months. There were no signs of habituation or addiction. We conclude that narcotics can be safely and successfully utilized for long-term management of phantom limb pain.
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Phantom Limb Pain: Implications for Treatment of Pathologic Pain
Ronald Melzack · Anesthesiology · 1971 · 213 citations · Full text
Analgesic activity of tricyclic antidepressants
Katharyn Spiegel, Robert G. Kalb, Gavril W. Pasternak · Annals of Neurology · 1983 · 166 citations