Concepedia

Synthesis of Phthalocyanines−ALA Conjugates: Water-Soluble Compounds with Low Aggregation

Kléber T. de Oliveira, Francisco F. de Assis, Anderson Orzari Ribeiro, Claudio Neri, Adjaci Uchôa Fernandes, Maurı́cio S. Baptista, Norberto Peporine Lopes, Osvaldo Antônio Serra, Yassuko Iamamoto

The Journal of Organic Chemistry · 2009 · 44 citations · 52 references

DOI

Concepts

Abstract

Syntheses of two water-soluble phthalocyanines (Pc) containing 5-aminolevulinic acid (ALA) linked to the core structure are described. These compounds were prepared by using original functionalizations, and they present remarkable structural and photophysical features, indicating that they could be applied to photodynamic therapy (PDT).

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