JAMA · 1964 · 20 citations · 2 references
PharmacyPharmaceutical AnalysisPharmacologyDosage Form DesignDrug DiscoveryDrug InformationDosage Form ExaminationDrug AuthenticationDrug IdentificationSolid Dosage FormsDosage Form CharacterizationDosage Form IdentificationDosage Form InterpretationDrug Product IdentificationPediatric Dosage FormsPharmaceutical Product IdentificationSolid Dosage Form AnalysisUnknown Substance Identification
INITIATED BY HEFFERREN, the monumental task of making available to physicians and others an "Identification Guide for Solid Dosage Forms" reached culmination with the publication of the Dec 22, 1962, issue ofThe Journal.<sup>1</sup>Basing specificity on contrasts in physical characteristics, the Guide provides for the formation of a ten-digit code number for an unknown drug; the code number is then able to be matched with those of approximately 5,000 solid drug forms. When necessary, further differentiation can be accomplished by dimensional measurements (0.1 mm) in each of three planes, attention to imprints, etc. The question immediately posed itself, "<i>In the field</i>, will this method be as effective as intended?" We sought an answer in the following manner. <h3>Method</h3> Initially, 30 junior medical students and nine staff pediatricians ( group A ) were each confronted with three unknown medications—two tablets and one capsule. Each was also provided with a copy of
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THE LABELLING OF PHARMACEUTICAL PREPARATIONS
Wesley Collier · The Lancet · 1962 · 13 citations