Some Toxicological Aspects of Stannous Fluoride After Ingestion as a Clear, Precipitatefree Solution Compared to Sodium Fluoride

Abstract

Weanling rats were administered 20, 380, and 20,000 ppm F as clear precipitatefree SnF2 solutions. Equivalent ppm F as NaF solution was similarly administered for comparison. The rats were autopsied at the end of the study for histological examination of kidney, liver, and incisors. The pathognomonic manifestations were correlated with the plasma F levels.