Nature · 1979 · 399 citations · 13 references
Life SciencesImmunologyMonoclonal AntibodiesHybridoma TechnologyHybridoma-derived AntibodiesMyeloma Cell Lines
13
Continuous cultures of fused cells secreting antibody of predefined specificity
Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations
Pharmacy, Cell Biology, Immunology +11
Antibodies to major histocompatibility antigens produced by hybrid cell lines
G. Galfré, Sebastian Howe, César Milstein et al. · Nature · 1977 · 1.7K citations