Dalton Transactions · 2008 · 120 citations · 77 references
Natural SciencesChemical EngineeringChemistryCatalysisOrganic ChemistryReaction EngineeringCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MechanismsMicrowave-assisted SynthesisOrganic SynthesisBorylation ReactionsCatalyst Precursor DesignCatalytic SynthesisDehydrogenation CatalysisHydrogenationMicrowave-assisted CatalysisMicrowave-assisted Catalyst SynthesisSelective Synthesis
We present herein a high yield, highly selective catalytic synthesis of vinylboronate esters (VBEs), including 1,1-disubstituted VBEs, from alkenes without significant hydrogenation or hydroboration, using the simple catalyst precursor, trans-[RhCl(CO)(PPh3)2] (1), and the diboron reagents B2pin2 (2a, pin = pinacolato = OCMe2CMe2O) or B2neop2 (2b, neop = neopentylglycolato = OCH2CMe2CH2O), or the monoboron reagent HBpin, all of which are commercially available. The reactions were conducted at 80 degrees C using conventional heating, or in a microwave reactor at 150 degrees C.
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