α-Hydroxylation of N-nitrosopyrrolidine and N′-nitrosonornicotine by human liver microsomes

[Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

H. Druckrey, R. Preußmann, S. Ivanković et al. · PubMed · 1967 · 1.4K citations

Pharmacy, Pharmacology, Toxicology +8

Tobacco-Specific Nitrosamines: Formation From Nicotine In Vitro and During Tobacco Curing and Carcinogenicity in Strain A Mice 2 3

Stephen S. Hecht, Chi-hong B. Chen, Norio Hirota et al. · JNCI Journal of the National Cancer Institute · 1978 · 149 citations

Medicine, Pharmacology, Toxicology +13

The use of new methods to measure: The effect of diet and inducers of microsomal enzyme synthesis on cytochrome P-450 in liver homogenates, and on metabolism of dimethyl nitrosamine

AndréE.M. McLean, Pauline Day · Biochemical Pharmacology · 1974 · 130 citations

Medicine, Biochemistry, Toxicology +15

Assessment of tobacco-specific N-nitrosamines in tobacco products.

Dietrich Hoffmann, John Adams, Klaus D. Brunnemann et al. · PubMed · 1979 · 126 citations

Pharmacy, Toxicology, Analytical Toxicology +12

<i>N</i> ′-Nitrosonornicotine in Tobacco

Dietrich Hoffmann, Stephen S. Hecht, Raphael M. Ornaf et al. · Science · 1974 · 117 citations

Pharmacy, Toxicology, Cancer Prevention +7