The effects of modulation of calcium influx through the voltage-sensitive calcium channel on cardiomyocyte hypertrophy

Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels

Matthias Schramm, G. Thomas, R. Towart et al. · Nature · 1983 · 1K citations

Novel Dihydropyridines, Biochemistry, Medicine +6

Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response.

P. Simpson · Journal of Clinical Investigation · 1983 · 616 citations · Full text

Cardiac Muscle, Myocyte Size, Cellular Physiology +19

Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction. Evidence for independent regulation of growth and beating.

Paul Simpson · Circulation Research · 1985 · 485 citations · Full text

Cardiac Muscle, Heart Failure, Alpha 1-Adrenergic Receptor +18

Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Cross-striations, ultrastructure, and chronotropic response to isoproterenol.

Paul Simpson, Shoshana Savion · Circulation Research · 1982 · 452 citations

Cardiac Muscle, Heart Failure, Cardiac Progenitor Cells +20

Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholamines.

Paul Simpson, Aiden McGrath, Shoshana Savion · Circulation Research · 1982 · 422 citations

Cardiac Muscle, Heart Failure, Myocardial Cell Hypertrophy +18