Science · 1968 · 93 citations · 5 references
Life SciencesNeurosciencePhysiologyNeuroendocrinologyGrowth HormoneGrowth Hormone RegulationHormone ReleaseHormone SecretionHypothalamic-pituitary AxisHypothalamic-pituitary RegulationHypothalamic FunctionHypothalamic Hormone SecretionHypothalamic HormonesHypothalamic NeurosecretionHypothalamic-pituitary SignalingHypothalamic-pituitary-growth AxisHypothalamic-pituitary-somatotropic AxisVentromedial Nucleus
Stimulation of the ventromedial hypothalamic nucleus in rats resulted in increased plasma growth hormone levels within 5 minutes, as measured by radioimmunoassay. Stimulation of the cerebral cortex was without effect. These observations confirm previous results involving destructive lesions and establish the ventromedial nucleus as a hypothalamic locus involved in the control of growth hormone secretion.
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