Effects of physical therapy intervention for children with acute lymphoblastic leukemia

TLDR

Children with acute lymphoblastic leukemia often experience reduced mobility during treatment, raising concerns about long‑term functional outcomes. The study aimed to evaluate the impact of a structured physical therapy program on joint mobility and muscle strength in these children. Twenty‑eight children aged 4–15 were randomized to receive five supervised PT sessions plus a home exercise program of ankle dorsiflexion stretching, lower‑extremity strengthening, and aerobic activity, while controls received standard care. Four months after intervention, children in the PT group showed significantly greater ankle dorsiflexion range of motion and knee extension strength, with no other functional differences, indicating that PT improves key gait‑related functions. © 2003 Wiley‑Liss, Inc.

Abstract

Abstract Background The purpose of this study was to examine the effects of physical therapy intervention in children with acute lymphoblastic leukemia (ALL). Procedure Twenty‐eight children aged 4–15 years were randomly assigned to an intervention or control group. The intervention group received five sessions of physical therapy and was instructed to perform an individualized home exercise program consisting of ankle dorsiflexion stretching, lower extremity strengthening, and aerobic exercise. Results After 4 months children who received physical therapy intervention had significantly improved ankle dorsiflexion active range of motion and knee extension strength ( P < 0.01). Differences were not found between the two groups for any of the other dependent variables. Conclusions Physical therapy intervention for children with ALL receiving maintenance chemotherapy improved two body functions important for normal gait. Physical therapy programs initiated earlier in treatment and with greater emphasis on endurance activities may also improve stamina and quality of life (QOL). © 2003 Wiley‐Liss, Inc.