The Analgesic Effect of Fentanyl, Morphine, Meperidine, and Lidocaine in the Peripheral Veins

Abstract

Propofol, a commonly used anesthetic, often causes pain on injection. Given as venous retention pretreatments 1 min before propofol, meperidine and lidocaine were found to significantly reduce the propofol injection pain, whereas fentanyl and morphine only slightly reduced the propofol injection pain.