Cancer Biology & Therapy · 2003 · 157 citations · 0 references
MedicineOncologyPharmacologyCancer PharmacologyChemotherapyPharmacodynamicsAdverse Effects Of ChemotherapyChemotherapy ResistanceCytotoxic ChemotherapyOncology PharmacologyPharmacodynamics Of Anticancer AgentsPharmacokinetics Of Anticancer DrugsAnticancer ChemotherapyChemotherapeutic ToxicologyChemotherapy PharmacodynamicsChemotherapy-induced ApoptosisChemotherapy-related ToxicityMolecular Drug ResistancePharmacokinetics Of Cytotoxic ChemotherapyTherapeutic Window Determination
Chemotherapy can be best used by understanding the principles of pharmacology, tumor biology, cellular kinetics and drug resistance. Here we try to focus on the major classes of chemotherapeutic drugs, their mechanisms of action, toxicities; and the therapeutic window.